Beschreibung

■■ Comparison of tablet presses for production based on different formulations
■■ Hands-on experiences
■■ Sound knowledge transfer by well-known speakers

Dedicated lectures dealing with:
■■ Formulations
■■ Mechanical properties
■■ Compression and compaction theory
■■ Process induced transformations
■■ Excipients
■■ Data acquisition
■■ Compaction simulators
■■ Predictability of tablet properties
■■ Technical concepts of tablet presses

Committee
■■ Peter Kleinebudde
Emeritus professor, Heinrich Heine University Düsseldorf
■■ Markus Thommes, Technical University Dortmund

Zielsetzung

Tablets are the most important and most common form of medicine worldwide. In the past few years scientific knowledge has emerged, especially in the field of tablets, which allows us to turn from the „art of tableting“ to a knowledge-based development and production of tablets. On this basis the participants will be offered the basics of formulation development and the production of tablets.
In small groups the internship is conducted under the supervision of experienced instructors on various production presses. Each participant will actively participate in trials for the production of tablets and various methods for their characterization. On the basis of selected examples, typical approaches and solutions are shown, which are subsequently discussed in detail.
Modelling approaches for different production presses will be presented.
At the end of the course, the participants should have basic knowledge about the solution of tableting tasks.
The focus is on the natural sciences and engineering aspects of tableting. Regulatory aspects, such as cleaning or validation are not dealt with.