Making science work

Description

■■ Comparison of tablet presses for production based on different formulations
■■ Hands-on experiences
■■ Sound knowledge transfer by well-known speakers

Dedicated lectures dealing with:
■■ Formulations
■■ Mechanical properties
■■ Compression and compaction theory
■■ Process induced transformations
■■ Excipients
■■ Data acquisition
■■ Compaction simulators
■■ Predictability of tablet properties
■■ Technical concepts of tablet presses

Committee
■■ Peter Kleinebudde
Emeritus professor, Heinrich Heine University Düsseldorf
■■ Markus Thommes, Technical University Dortmund

Objective

Tablets are the most important and most common
form of medicine worldwide. In the past few years
scientific knowledge has emerged, especially in the
field of tablets, which allows us to turn from the „art
of tableting“ to a knowledge-based development and
production of tablets. On this basis the participants will
be offered the basics of formulation development and
the production of tablets.
In small groups the internship is conducted under
the supervision of experienced instructors on various
production presses. Each participant will actively
participate in trials for the production of tablets and
various methods for their characterization. On the basis
of selected examples, typical approaches and solutions
are shown, which are subsequently discussed in detail.
Modelling approaches for different production presses
will be presented.
At the end of the course, the participants should have
basic knowledge about the solution of tableting tasks.
The focus is on the natural sciences and engineering
aspects of tableting. Regulatory aspects, such as
cleaning or validation are not dealt with.