APV basics: Preformulation | KN 6722
Veranstaltungsort
Park Inn by Radisson Brussels AirportGrentstraat 3
1831 Brussels (Diegem)
Tel.:+32 2 302 75 00
Fax:+32 2 302 75 99
Kursprogramm zum Download
- 6722 Preformulation.pdf(617 K)
Zielgruppe
This short course is intended to provide a useful background on contemporary solid state and solution characterization of API’s as well as to provide a framework for translating these data into useful formulations. The course is designed to be useful to both scientists new to the field as well as the experienced pharmaceutical researcher with an eye towards the state of the art and future direction.
Zielsetzung
Preformulation is an essential step in the pharmaceutical development of an API. It is the process by which candidate drugs are characterized with respect to the appropriateness to be formulated and processed to a useful dosage form. During this phase of the development, information about the physicochemical properties (e.g., solubility, ionization behavior, solid state properties,…), biopharmaceutical properties (e.g., permeability through bio-membranes) and stability profile (physical, chemical, compatibility with excipients, etc.) of the drug candidate is collected. This information guides the formulation scientist as it will dictate many of the possible formulation and processing approaches.
Referenten
Guy van den Mooter
Guy Van den Mooter (°1964) obtained his Ph.D. in 1994 (university of Leuven ‐ KU Leuven,
pharmaceutical technology). Following a position as scientist at Janssen Research Foundation, he obtained a post‐doctoral position at the laboratory for Pharmacotechnology and Biopharmacy at the university of Leuven. In 1999 he was appointed as assistant‐professor, and since 2009 he is full professor at the faculty of Pharmaceutical Sciences in the Drug Delivery and Disposition research group. The focus of his research group is the formulation, process development and physical chemistry of drug‐polymer solid dispersions, nanocrystals and mesoporous silica drug delivery systems. The main objective is to explore the relationship between the formulation, the process applied and the performance in terms of stability and drug release. He has published over 200 scientific papers in international peer‐reviewed journals.
He teaches courses of pharmaceutical technology, preformulation and physical chemistry in
undergraduate and graduate programs. He is coordinator of the master program in industrial pharmacy.
He is member of the Belgian Pharmacopeia commission and member of the editorial board of several scientific journals. In 2007, he founded FORMAC Pharmaceuticals, a drug delivery company focused on the formulation of poorly soluble active pharmaceutical ingredients using unique mesoporous silica materials.
Geert Verreck
Dr. Geert Verreck is a Scientific Director and Fellow in Drug Product Development at Janssen R&D in Beerse, Belgium. His expertise is in the area of oral solid development, from preformulation to early and late development as well as transfer to commercial manufacturing. Dr. Verreck specifically has expertise in enabling technology platforms such as hot melt extrusion, spray drying, bead coating, supercritical fluid technology and nanotechnology (particle size reduction via milling and electrostatic spinning). He started working for J&J in 1995 after graduating as a chemical engineer. In 2005 he received his Ph.D. in Pharmaceutical Sciences at the Catholic University of Leuven, Belgium. He has published 34 peer reviewed journal articles as author or co-author and holds 8 patents in the area of solid dispersions. Dr. Verreck also presented approximately 85 meeting abstracts and delivered approximately 50 oral presentations. He is also the recipient or co-recipient of various recognitions including the ISASF (International Society for the Advancement of Supercritical Fluids) PhD thesis award (2005), the J&J Philip B. Hofmann Award (2006), the J&J Business Excellence Award (2008), the J&J Standards of Leadership Award (2009).
Preise
Kategoriepreis | |
---|---|
Industry | 1.290,00 € |
Academia/Authorities | 645,00 € |
Full time students | 178,00 € |
Veranstalter
APV-Geschäftsstelle
Dr. Martin Bornhöft
Tel.: +49 6131 9769-0
Fax: +49 6131 9769-69
E-Mail: apv@apv-mainz.de
www: https://www.apv-mainz.de/